Is it possible to predict diffuse obliterative otosclerosis preoperatively by audiologic examination
Patients with diffuse obliterative otosclerosis have more extensive footplate pathology than annular cases. As a result of this more skill is required for diffuse otosclerosis cases, and postoperative hearing results are usually worse than annular cases. In this retrospective study we compared the preoperative audiological features of annular and diffuse otosclerosis patients. The subjects were […]
Hearing Loss in Biotinidase Deficiency: Genotype-Phenotype Correlation
Children with symptoms of profound biotinidase deficiency with null mutations are more likely to have hearing loss develop than those with missense mutations, even if not treated for a period of time. Hearing loss appears to be preventable in children with null mutations if treatment is initiated soon after birth.
Bony sheathed chorda tympani: A unique case of incudomalleolar fixation
To describe a unilateral conductive hearing loss caused by restriction of the movements of malleus and incus due to chorda tympani in a bony sheath. A 23-year-old man with a stable mild conductive hearing loss in the left ear and mild sensorineural hearing loss in the right ear. An exploratory tympanotomy was performed. Immobility of […]
SLC26A4 mutations are associated with a specific inner ear malformation
Inner ear anomalies have been reported in approximately 30% of children with early onset deafness. Identification of causative genetic factors in a large proportion of these patients was not successful. Mutations in the SLC26A4 gene have been detected in individuals with enlarged vestibular aqueduct (EVA) or Mondini dysplasia. We aimed to characterize the inner ear […]
Benign paroxysmal positional vertigo in swimmers
This study was designed to evaluate the relationship between swimming and benign paroxysmal positional vertigo (BPPV). This prospective study was comprised of 30 subjects (15 females, 15 males, mean age 15.6 years; range 11 to 23 years) who had been swimming regularly for at least two years. Twenty subjects (9 females, 11 males; mean age […]
Surgical Results of Cochlear Implantation in Malformed Cochlea
To report the surgical aspects of cochlear implantation in malformed cochlea. Tertiary care center. Retrospective case review. Between November 1997 and October 2004, 20 patients with inner ear malformations were implanted in our department. The age range was between 2 and 37 years (average, 8.8 yr). The anomalies were classified according to Sennaroglu and Saatci […]
Pneumolabyrinth following traumatic luxation of the stapes into the vestibule
Pneumolabyrinth can result from traumatic luxation of stapes into the vestibule. The diagnosis of stapes luxation following a head injury can be delayed especially if the otoscopic examination is within normal limits. Here a 15-year-old girl presenting with vertigo and nystagmus following a blunt head injury was presented, whose computerized tomography revealed air in the […]
Otitic hydrocephalus: Role of radiology for diagnosis
The pathogenesis of otitic hydrocephalus remains unclear. The use of radiological examination is very important to clarify both the diagnosis and the pathogenesis. In this article the role of magnetic resonance imaging (MRI) and magnetic resonance venography (MRV) is discussed. Two patients with the diagnosis of otitic hydrocephalus and their MRI and MRV findings are […]
Identification of an ancestral haplotype of the 35delG mutation in the GJB2 (connexin 26) gene responsible for autosomal recessive non-syndromic hearing loss in families from the Eastern Black Sea Region in Turkey
Mutations in the GJB2 gene have been shown to be the major cause of autosomal recessively inherited, prelingual, non-syndromic hearing loss. 35delG was found to be the most frequent mutation among Caucasians. In this study, we performed haplotype analysis of two large families with autosomal recessive non-syndromic hearing loss (totally 33 affected, 37 unaffected) from […]
Unpartitioned Versus Incompletely Partitioned Cochleae: Radiologic Differentiation
In the process of evaluating our patients, we realized that the term “Mondini deformity” was being used to describe two different types of incomplete partition of the cochlea. THE First one consisted of an unpartitioned, completely empty cochlea where the interscalar septum and entire modiolus were absent, giving the cochlea a cystic appearance; a grossly […]
Petrous Anatomy for Middle Fossa Approach
The objective was to describe the relationship of anatomical landmarks required for the middle fossa approach to lesions of the petrous apex and internal auditory canal (IAC). Landmarks for safe identification of the IAC are defined, as are two zones (safe zones I and II) anterior and posterior to the IAC. Temporal bone anatomical study. […]
A New Classification for Cochleovestibular Malformations
The report proposes a new classification system for inner ear malformations, based on radiological features of inner ear malformations reviewed in 23 patients. The investigation took the form of a retrospective review of computerized tomography findings relating to the temporal bone in 23 patients (13 male and 10 female patients) with inner ear malformations. The […]
Magnetic resonance imaging versus computed tomography in pre-operative evaluation of cochlear implant candidates with congenital hearing loss
Recent reports indicate that the cochlear nerve may be absent in some cases of congenital sensorineural hearing loss. The aim of this prospective study was to determine the incidence of cochlear nerve anomaly in cochlear implant candidates with congenital hearing loss using magnetic resonance imaging (MRI). Twenty-seven patients with congenital profound bilateral sensorineural hearing loss […]
Anteroposterior Approach with Split Ear Canal for Cochlear Implantation in Severe Malformations
To present an anteroposterior approach with split ear canal technique in severe malformed ears in which cochlear implantation is not possible through the standard facial recess approach. The operation was performed at Hacettepe University Medical Faculty, which is a tertiary care center. Case report. A 4-year-old female patient with severe Mondini malformation whose facial nerve […]
Intratympanic Dexamethasone, Intratympanic Gentamicin, and Endolymphatic Sac Surgery for Intractable Vertigo in Meniere’s Disease
To compare the efficacy of intratympanic dexamethasone (ID), intratympanic gentamicin (IG), and decompression of the endolymphatic sac (ESD) for intractable vertigo in Meniere’s disease. This prospective study was conducted at Hacettepe University Medical Faculty, a tertiary care center. Dexamethasone was applied through a ventilation tube in 24 patients, intratympanic gentamicin (also through a ventilation tube) […]
Cochlear Implants: Is There Any Relationship between Stimulation Rates and Adaptation?
To determine the relationship between stimulation rate and adaptation in cochlear implant users. A prospective clinical study. This study was conducted at Hacettepe University Medical Faculty, which is a tertiary care and cochlear implant center in Ankara, Turkey. Seven patients (three women, four men) who were using Nucleus CI 24 M cochlear implants (Cochlear Corp., […]
Relationship of Vestibular Aqueduct and Inner Ear Pressure in M??ni??re???s Disease and the Normal Population
Etiopathogenesis of Ménière’s disease has not been resolved. The principal histopathologic finding in this disease is endolymphatic hydrops. The majority of radiologic and histopathologic studies demonstrated a narrow vestibular aqueduct in Ménière’s disease. There is no study in the literature investigating the relationship between inner ear pressure and vestibular aqueduct dimensions. Static acoustic compliance is […]
Relationship of the Cochlear Aqueduct and Inner Ear Pressure in M??ni??re’s Disease and in a Normal Population
The aim of this study was to determine the dimensions of cochlear aqueduct radiologically in patients with Ménière’s disease and in normal subjects, and to correlate these findings with normal and low static acoustic compliance (SAC) (high and normal perilymphatic pressure) to see whether the dimensions of the cochlear aqueduct play any role in the […]